Does Prolia cause hair loss? Shortness of breath is just the beginning. If a pressure fracture due to osteoporosis exists, treatment should be conducted to prevent a new fracture. This in turn puts more pressure on the vertebrae and others may fracture, worsening the situation. to reduce the risk of fractures in people who have multiple myeloma , and in people who have certain types of cancer that began in another part of the body but has spread to the bones. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. I will just continue doing my exercises of walking and yoga. It is estimated in the UK that 2% of women aged 50 years have the condition and this rises to 25% by the age of 80. I am due for my next shot of prolia in June which I am gone cancel. However, bone growth is slower in people with osteoporosis, and healing may take longer. I know the side effects that I had cannot be the norm and am not going to go through the pain again. 2022 eHealthMe.com. 3. 9. Use a backpack or other type of bag that leaves your hands free. And during the first month or more following Prolia, I had a lot of medical problems, which finally went away. Back pain is found among people who take Prolia, especially for people who are female, 60+ old, have been taking the drug for < 1 month. To me it do cause pain in different ways.Also swelling in feet and ankles for me.Will not take again. Hello , we have a lot of members discussing Prolia treatment in this discussion, . Keep areas outside in good repair and free of clutter. I had and (based on the pain that I still have) currently have bilateral sacral insufficiency fractures and bilateral pubic insufficiency fractures; I roll over and my bones crunch. Thank for your help! Nerve roots can become compressed by the collapse of the spine, causing sciatica and other nerve pain. When a compression fracture occurs, the discs that are between the vertebrae that provide cushioning become compressed. Mild side effects that have been reported with Prolia include: pain in bones* and muscles, including back, arm, and leg pain; joint pain; constipation; These side effects may be temporary, lasting a few days or weeks. My Doctor wanted me to take Prolia, I said no because I was afraid of the side effects, he told me I had no choice, that's when I found another Doctor, you do have the right to refuse, then I called and spoke with a nurse at Prolia, she said anyone who already had medical problems she would not advise to take it, there are others. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Thank you. I am sure the Prolia caused this and many other unpleasant side effects. We study millions of patients and 5,000 more each day. Mild side effects that have been reported with Prolia include: These side effects may be temporary, lasting a few days or weeks. These side effects may go away during treatment as your body adjusts to the medicine. Fractures can take months to heal. And eat healthy while taking calcium supplements. Again, I encourage you to contact FDA about your side effects caused by Prolia. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. When the problem strikes the vertebrae in your spine, it can lead to considerable back pain. It is also important information to carry with you in case of emergencies. Meanwhile the pain in my jaw / behind my ear is not going away and I keep on taking Mobic and muscle relaxers. In most people, fractures cause pain for six to eight weeks after they occur. Osteoporosis symptoms can cause pain and discomfort. Mine are bad? * Multiple myeloma is type of cancer that affects your white blood cells. As fractures tend to heal slowly in people who have osteoporosis this may lead to deformities such as curvature of the spine. I would like to invite , , , , and to share any side-effects they, or a loved one, had or didnt have while taking Prolia. Prolia and Xgeva both contain the same active drug called denosumab. Another way to report it to the FDA is to report it to the FDA hotline at 1-800-332-1088. In other words, the drug offered no lasting benefit. Other drugs that have the same active ingredients (e.g. It could be caused by a muscle injury or weakness, for example, or by degenerating discs between vertebrae. We study millions of patients and 5,000 more each day. The bottom line is that if you are uncomfortable with your doctor's diagnosis, you should seek a second opinion. Prolia (denosumab) is a drug for osteoporosis that works by blocking a receptor ligand called rankl. The most common adverse reactions reported with Prolia in patients with glucocorticoid-induced osteoporosis are back pain, hypertension, bronchitis, and headache. Best to you. The use of the eHealthMe site and its content is at your own risk. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. . are at high risk for fracture, meaning women who have had a fracture related to osteoporosis, or who have multiple risk factors for . The MRI was normal and I finally got my first shot of Botox 3 days ago the effect takes about two weeks to take place . There could also be a physical cause of the back pain that is unrelated to osteoporosis, a disease in which the bones lose density and become fragile. The use of the eHealthMe site and its content is at your own risk. Check whether Back pain is associated with a drug or a condition. It is based on denosumab (the active ingredients of Prolia) and Prolia (the brand name). You may want to avoid sleeping on your stomach because it can . If you have questions about which medication is right for you, talk with your doctor. Most vertebral compression fractures are treated nonsurgically, such as with rest, pain medications, or applying ice and/or heat while the fracture eventually heals on its own. If so, do you have any helpful remedies? Osteoporosis causes bones to become thinner and break more easily. 2022 eHealthMe.com. This results in pain in the back of the affected person and can also lead to Osteoporosis Pain in Shoulders and Osteoporosis Pain in Feet. Some reports may have incomplete information. Is Prolia worth the risk? The most common side effects of Prolia in men with osteoporosis are back pain, joint pain, and common cold (runny nose or sore throat). Number of reports submitted per year: Severity of Back pain *: least: 10 % moderate: 50 % severe: 30 % most severe: 10 % When people recovered from Back pain *: while on drug: 20 % after off the drug: 20 % not yet: 60 % Effectiveness of Prolia *: not at all: 25 % Denosumab injection (Prolia) is used treat osteoporosis that is caused by corticosteroid medications in men and women who will be taking corticosteroid medications for at least 6 months and have an increased risk for fractures or who cannot take or did not respond to other medication treatments for osteoporosis. Although the first 8 months after the Prolia, I did have sky high levels of my parathyroid. Talk with your doctor if any of these apply to you, or if you have questions. You shouldnt take Prolia and Xgeva at the same time. Can Prolia affect your teeth? Lower back or side pain. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Subsequently, this causes pain and potential problems with ambulation. It is created by eHealthMe based on reports of 137,760 people who have side effects when taking Prolia from the FDA, and is updated regularly. This has continued for over a year. Mine hurt so bad I can hardly move? Either lack of sunlight or a diet poor in Vitamin D may lead to this condition. Microscopic fractures can lead to deep bone pain that some people with osteoporosis describe as feeling like a toothache. It can cause: Sudden, severe back pain that gets worse when you are standing or walking with some relief when you lie down; It was approved in 2010 by the FDA with much fanfare because it's a monoclonal antibody that targets the "key" (RNKL) that fits into the receptor "lock" (RANK). You can develop osteoporosis anywhere in your body, but the condition is most likely to affect your hips, spine, and wrists. Prolia helps stop the development of bone-removing cells before they can reach the bones and cause damage. A car accident, sports injury, a fall or lifting a heavy object can lead to a sprain, muscle spasm or fracture and cause pain in the back. It could be. Also remember to take your time. Osteoporosis is a condition where the bones become thin and weak due to loss of bone minerals. For severe kyphosis, spinal reconstructive surgery may take the pressure off a pinched nerve and stabilize the spine. Swelling can cause weight to increase. The #1 Cause of Lower Back Pain, Say Doctors - There's several types of back pain and lumbago is a general term to describe lower back pain symptoms and can be felt in the. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Wish you the best. I've lost about 8 pounds. Just go to the FDA website. Trouble twisting or bending your body, and pain when you do. Note: After the Food and Drug Administration approves a drug, it tracks and reviews side effects of the medication. Some women (and men) experience higher cholesterol levels when taking Prolia. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. I am certain that my bone pain was caused by Prolia. Reported by a physician from United States on 2012-06-14 Patient: 60 year old female, weighing 64.0 kg (140.8 pounds) Dosage of drugs is not considered in the study. To SHEsevEN4, That really amazes me that the nurse at Prolia told you that. Diabetic Drugs That Cause Osteoporosis. The phase IV clinical study analyzes which people take Prolia and have Chest pain. it is believed that syndrome is a physical manifestation of psychological stress), Tendonitis (a condition that causes pain and swelling of tendons), The flu (the flu is caused by an influenza virus), Thrombocytopenia (decrease of platelets in blood), Thrombosis (formation of a blood clot inside a blood vessel), Tibia fracture (fracture of lower leg bone), Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)), Traumatic injury of the bladder and urethra, Tremor (trembling or shaking movements in one or more parts of your body), Urinary incontinence (inability to control the flow of urine and involuntary urination), Urticaria (rash of round, red welts on the skin that itch intensely), Wheezing (a high-pitched whistling sound made while you breath), Back pain in Pfizer BioNTech Covid Vaccine, Back pain in Johnson and Johnson Covid Vaccine, Age-related macular degeneration (armd or amd), Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension, Anxiety disorder due to a general medical condition, Attention deficit disorder with hyperactivity, Attention deficit disorder with hyperactivity (addh), Attention deficit hyperactivity disorder (adhd), Chronic thyroiditis (hashimoto's disease), Drowsiness, hypersomnia, sleepiness - during the day, somnolence, Exhaustion, fatigue, lethargy, tiredness, weariness, Idiopathic diffuse interstitial pulmonary fibrosis, Idiopathic thrombocytopenic purpura (itp), Inflammatory bowel disease - crohn's disease, Inflammatory bowel disease - ulcerative colitis, Lack of strength, muscle weakness, weakness, Sleep disorder due to a general medical condition, Sleep disorder due to general medical condition, insomnia type, Claritin and Alendronate Sodium drug interaction, Hydroxychloroquine Sulfate and Vaginal Yeast Infection, Pain and drugs of ingredients of mefloquine hydrochloride, Irbesartan and C-Reactive Protein Increased. 7. when your pain with is gone listen to your body its telling you start more strength training exercise ,water aerobics or just chair exercise .My girlfriend who has osteoporosis went to Dr ,the shot about killed her, Dr put her on high dose of Vit D3 and exercise that was 10 yrs ago she still does today the VitD3is normal dose but she keeps up with exercise now and travels all over the world still .You are your own advocate ,you know best for your body. The phase IV clinical study analyzes which people take Prolia and have Back pain. The study uses data from the FDA. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. This is in no way a complete list of things that you can do to help prevent falls, but this is a starting point. Although osteoporosis is the most common cause of this type of fracture, there are other causes: Trauma to the back (car accidents and sports injuries) Tumors that start in the bones or spread to the bone from elsewhere (liver, prostate cancer) Tumors that start in the spine, such as multiple myeloma (cancer of the bone marrow) Symptoms. Pain from this can be challenging to manage effectively, and this severe damage may require surgery. Magnesium and vitamin D3 work to each other's advantage to promote healthy bones. Weight gain wasnt reported as a side effect in studies of people using Prolia. . Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to denosumab: subcutaneous solution, Also Check: Exercise For Lower Back Pain Mayo Clinic. Use only non-skid items if you have mats, carpets or area rugs. We study how severe was Back pain, when it was recovered, drug effectiveness, race, and more among people who take Prolia. I had prolia injection a week ago. And as disclosed on the Prolia website (https://www.prolia.com), it can cause serious side effects because it "is a medicine that may affect your immune system" (remember the cytokines?). Im still dealing with my horrible side effects 2 and a half years later after getting just one Prolia injection. Your doctor will order certain tests to be sure it is safe for you to receive denosumab injection and to check your bodys response to denosumab injection. preventing certain bone problems in people with, preventing certain bone problems in people with cancer that has spread to their bones. My question is does anyone know how long these side effects last and when finally I will be pain free and have my life back ? There typically are no symptoms in the early stages of bone loss. Our phase IV clinical studies alone cannot establish cause-effect relationship. But for the rest of the forum, does anyone else have this problem? If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. (A placebo is a treatment with no active drug.) All information is observation-only. Prolia information for Healthcare Professionals. We comply with the HONcode standard for trustworthy health information. Loginask is here to help you access does prolia cause joint pain . Muscles can spasm, cramp, and pinch nerves as they contract to try to protect fragile joints and bones. skin-related side effects, such as rash . Indication: Osteoporosis Postmenopausal The bone mass loss increases your risk of fractures, deformity, and severe pain. People with osteoporosis can also experience pain that is caused by another condition, either one that is related to their osteoporosis or separate and unrelated. It can be detected with a simple scan, known as a DEXA*. Been going to rehab for my back, it feels OK for awhile then the pain returns. I tried to friend you, in case you only want a private conversation about it. Check whether Back pain is associated with a drug or a condition, Back pain and drugs with ingredients of denosumab, Agitation (state of anxiety or nervous excitement), Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection), Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death), Angioedema (rapid swelling of the dermis), Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat), Arthritis (form of joint disorder that involves inflammation of one or more joints), Aseptic necrosis (the death of bone tissue due to a lack of blood supply), Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles), Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure), Bronchitis (inflammation of the mucous membrane in the bronchial tubes), Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder), Cataract (clouding of the lens inside the eye), Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe), Compression fracture (fracture due to pressure caused by injury), Crohn's disease (condition that causes inflammation of the gastrointestinal tract), Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis), Dehydration (dryness resulting from the removal of water), Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it), Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall), Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters), Exostosis (formation of new bone on the surface of a bone), Fainting (loss of consciousness and postural tone), Femoral neck fracture (neck of femur bone fracture), Fibromyalgia (a long-term condition which causes pain all over the body), Flatulence (flatus expelled through the anus), Fluid retention (an abnormal accumulation of fluid in the blood), Foot deformity (functional disability of foot), Gallstones (stone formation by bile component), Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus), Gastrointestinal disorder (functional problems of gastrointestinal tract), Gastrointestinal haemorrhage (bleeding gastrointestinal tract), General physical health deterioration (weak health status), Glaucoma (increased fluid pressure in the eye with vision loss), Haematochezia (passage of stools containing blood), Hallucinations (sensations that appear real but are created by your mind), Heart palpitations (feelings or sensations that your heart is pounding or racing), Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle), Humerus fracture (injury to the upper arm bone), Hypercalcaemia (elevated calcium (ca+) level in the blood), Hyperhidrosis (abnormally increased sweating), Hyperkalemia (damage to or disease of the kidney), Hyperlipidaemia (presence of excess lipids in the blood), Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium), Hypoaesthesia (reduced sense of touch or sensation), Hypoaesthesia oral (reduced sense of touch or sensation in mouth), Hypocalcaemia (levels of calcium in blood serum are abnormally low), Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration), Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood), Hypotension (abnormally low blood pressure), Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development), Injection site erythema (redness at injection site), Injection site pruritus (severe itching at injection site), Intervertebral disc degeneration (spinal disc degeneration), Intervertebral disc protrusion (spinal disc protrusion), Joint dislocation (a joint position is changed from normal position), Joint range of motion decreased (disease of joint movement), Leukopenia (less number of white blood cells in blood), Localised infection (infection at the single location), Local swelling (swelling at the site of some application of substance or injury), Lung neoplasm malignant (cancer tumour of lung), Lymph follicular hypertrophy (an increase in the size of the lymph node follicles), Macular degeneration (painless eye condition that leads to the gradual loss of central vision), Malaise (a feeling of general discomfort or uneasiness), Mastication disorder (disease of chewing food), Metastases to bone (cancer spreads to bone), Micturition urgency (urgency to pass the urine), Mobility decreased (ability to move is reduced), Muscle atrophy (a decrease in the mass of the muscle), Muscle strain (an injury to a muscle in which the muscle fibres tear), Musculoskeletal chest pain (pain in chest muscle or nerve or bones), Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves), Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves), Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves), Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves), Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels), Nasopharyngitis (inflammation of the nasopharynx), Nausea (feeling of having an urge to vomit), Neuropathy peripheral (surface nerve damage), Oral discomfort (pain or irritation in mouth), Osteoarthritis (a joint disease caused by cartilage loss in a joint), Osteonecrosis of jaw (death of bone of jaw), Osteopenia (a condition where bone mineral density is lower than normal), Osteoporosis (bones weak and more likely to break), Osteoporotic fracture (fracture due to weak bone), Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect), Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect), Pathological fracture (broken bone caused by disease), Pollakiuria (abnormally frequent passage of relatively small quantities or urine), Pruritus generalised (generalized itching), Psoriasis (immune-mediated disease that affects the skin), Pulmonary embolism (blockage of the main artery of the lung), Pulmonary oedema (fluid accumulation in the lungs), Renal impairment (severely reduced kidney function), Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease), Respiratory disorder (respiratory disease), Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints), Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder), Scab (a hard coating on the skin formed during the wound healing), Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve), Scoliosis (a medical condition in which a person's spine is curved from side to side), Seizures (abnormal excessive or synchronous neuronal activity in the brain), Sepsis (a severe blood infection that can lead to organ failure and death), Skin blushing/flushing (a sudden reddening of the face, neck), Skin exfoliation (removal of the oldest dead skin cells), Speech impairment (adult) (inability to speak (adult)), Spinal compression fracture (fracture due to spinal compression on bone), Spinal disorder (disease of spine a back bone), Spinal fracture (fracture in one of vertebrae), Spinal osteoarthritis (joint cartilage loss in spine), Stomatitis (inflammation of mucous membrane of mouth), Stroke (sudden death of a portion of the brain cells due to a lack of oxygen), Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue), Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. Mild side effects that have been reported with Prolia include: pain in bones * and muscles, including back, arm, and leg pain joint pain dizziness* high cholesterol levels * bladder or. Among them, 5,503 people (3.99%) have Back pain. Denosumab has proven effective at building bone density and reducing spine and hip fractures. Please help. It can be detected with a simple scan, known as a DEXA*. 6. Food for Thought: Diet and Nutrition for a Healthy Back, When To Go To The Hospital For Lower Back Pain, How To Lose Lower Back Fat And Love Handles, excess air or gas in the stomach or bowels, feeling of constant movement of self or surroundings, redness, pain, itching, burning, swelling, or a lump under your skin where the shot was given. Ignoring back pain and potential vertebral compression fractures may lead to bigger problems down the road, such as increased pain, tingling, numbness, weakness, and severe spinal deformity. The phase IV clinical study analyzes which people take Prolia and have Back pain. After reading the reviews I don't want to take Prolia.What am I going to do. The most common adverse reactions (>5% and more common than placebo) in men with osteoporosis are back pain, arthralgia, and nasopharyngitis. In fact, the most common cause of osteoporotic pain is a spinal compression fracture. Despite the Dr's claims, if you want off he is obligated as your health care provider to help you stop it and help you do so in a way that will not harm you. These causes of lower back pain are generally related to: 1. What causes lower back pain & when should I be worried? You might want to start with a medical evaluation, which could lead to your healthcare provider providing assistive devices. I feel I am being robbed of what we're meant to be the last few years of my useful life (age 76).HELP ! Would love to get some feedback for this problem. I do not believe that doctors really understand how the Prolia side effects can be so painful. I am certain that my bone pain was caused by Prolia. Did she have anything else to say? Osteoarthritis can also develop in the joints of the spine and cause pain. A very severe forward curve is called hyperkyphosis. Back pain and pain in the bones, muscles, or joints are common side effects of Prolia (Denosumab). Prolia has active ingredients of denosumab. 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